Evo

a 7B parameter AI model designed to understand and generate DNA sequences across multiple biological scales; the model, trained on 2.7 million prokaryotic and phage genomes, can process sequences up to 131 kilobases long while maintaining single-nucleotide resolution, enabling it to understand both molecular-level interactions and genome-wide patterns; Evo demonstrates superior performance in predicting and generating functional DNA, RNA, and protein sequences, including the first successful AI-generated CRISPR-Cas complexes and transposable systems that have been experimentally validated.